Symptom screening among HIV-infected pregnant women is acceptable and has high negative predictive v high negative predictive value for active tuberculosis
Gupta A, Chandrasekhar A, Gupte N, Patil S, Bhosale R, Sambarey P, Ghorpade S, Nayak U, Garda L, Sastry J, Bharadwaj R, Bollinger RC; Byramjee Jeejeebhoy Medical College–Johns Hopkins University Study Group
We evaluated tuberculosis (TB) screening among 799 human immunodeficiency virus (HIV)-infected pregnant women in India. Eleven (1.4%) had active TB. The negative predictive value of screening using cough, fever, night sweats, or weight loss was 99.3%. Tuberculin skin test and targeted chest radiography provided no substantial benefit. TB symptom screening, as recommended by the World Health Organization, is effective for ruling out TB in HIV-infected pregnant women.
Clin Infect Dis. 2011 Nov;53(10):1015-8. doi:10.1093/cid/cir605. Epub 2011 Sep 21. PubMed PMID: 21940417; PubMed Central PMCID: PMC3193828